uni-leipzig-open-access/json/s10354-022-00952-z

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We performed a\u00a0survey in Austria and Germany to assess the use of UVCs and PICCs in preterm infants with a\u00a0birth weight &lt;\u202f1250\u202fg and associated rates of catheter-related adverse events.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Electronic survey of participating centers of the NeoVitaA trial. Main outcome parameter was the reported rates of UVC- and PICC-associated complications (infection, thrombosis, emboli, organ injury, arrhythmia, dislocation, miscellaneous).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 20\u00a0neonatal intensive care units (NICU) providing maximal intensive care in Austria and Germany (level\u00a0I) were contacted, with a\u00a0senior neonatologist response rate of 12\/20 (60%). The reported rates for UVC with a\u00a0dwell time of 1\u201310\u00a0days were bacterial infection: 4.2\u202f\u00b1\u20093.4% (range 0\u201310%); thrombosis: 7.3\u202f\u00b1\u20097.1% (0\u201320%); emboli: 0.9\u202f\u00b1\u20092.0% (0\u20135%); organ injury: 1.1\u202f\u00b1\u20091.9% (0\u20135%); cardiac arrhythmia: 2.2\u202f\u00b1\u20092.5% (0\u20135%); and dislocation: 5.4\u202f\u00b1\u20098.7% (0\u201330%); and for PICCs with a\u00a0dwell time of 1\u201314\u00a0days bacterial infection: 15.0\u202f\u00b1\u20093.4% (range 2.5\u201330%); thrombosis; 4.3\u202f\u00b1\u20093.5% (0\u201310%); emboli: 0.8\u202f\u00b1\u20091.6% (0\u20135%); organ injury: 1.5\u202f\u00b1\u20092.3% (0\u20135%); cardiac arrhythmia: 1.5\u202f\u00b1\u20092.3% (0\u20135%), and dislocation: 8.5\u202f\u00b1\u20094.6% (0\u201330%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The catheter-related complication rates reported in this survey differed between UVCs and PICCs and were higher than those reported in the literature. To generate more reliable data on this clinically important issue, we plan to perform a\u00a0large prospective multicenter randomized controlled trial investigating the non-inferiority of a\u00a0prolonged UVC dwell time (up to 10\u00a0days) against the early change (up to 5\u00a0days) to a\u00a0PICC.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s10354-022-00952-z","type":"journal-article","created":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T09:03:18Z","timestamp":1659949398000},"page":"161-167","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Umbilical venous catheter- and peripherally inserted central catheter-associated complications in preterm infants with birth weight &lt;\u202f1250\u00a0g","Nabelvenenkatheter- und periphere zentrale katheterassoziierte Komplikationen bei Fr\u00fchgeborenen mit einem Geburtsgewicht &lt;\u202f1250\u00a0g"],"prefix":"10.1007","volume":"173","author":[{"given":"Steffi","family":"Hess","sequence":"first","affiliation":[]},{"given":"Martin","family":"Poryo","sequence":"additional","affiliation":[]},{"given":"Ralf","family":"B\u00f6ttger","sequence":"additional","affiliation":[]},{"given":"Axel","family":"Franz","sequence":"additional","affiliation":[]},{"given":"Daniel","family":"Klotz","sequence":"additional","affiliation":[]},{"given":"Knud","family":"Linnemann","sequence":"additional","affiliation":[]},{"given":"Torsten","family":"Ott","sequence":"additional","affiliation":[]},{"given":"Johannes","family":"P\u00f6schl","sequence":"additional","affiliation":[]},{"given":"Michael","family":"Schroth","sequence":"additional","affiliation":[]},{"given":"Anja","family":"Stein","sequence":"additional","affiliation":[]},{"given":"Elisabeth","family":"Ralser","sequence":"additional","affiliation":[]},{"given":"Heiko","family":"Reutter","sequence":"additional","affiliation":[]},{"given":"Ulrich H.","family":"Thome","sequence":"additional","affiliation":[]},{"given":"Christian","family":"Wieg","sequence":"additional","affiliation":[]},{"given":"Anne","family":"Ehrlich","sequence":"additional","affiliation":[]},{"given":"Christian","family":"Ruckes","sequence":"additional","affiliation":[]},{"given":"Stefan","family":"Wagenpfeil","sequence":"additional","affiliation":[]},{"given":"Michael","family":"Zemlin","sequence":"additional","affiliation":[]},{"given":"Cihan","family":"Papan","sequence":"additional","affiliation":[]},{"given":"Arne","family":"Simon","sequence":"additional","affiliation":[]},{"given":"Johannes","family":"Bay","sequence":"additional","affiliation":[]},{"ORCID":"http:\/\/orcid.org\/0000-0001-6016-4558","authenticated-orcid":false,"given":"Sascha","family":"Meyer","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2022,8,8]]},"reference":[{"key":"952_CR1","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1097\/00129804-200611000-00005","volume":"29","author":"P Nash","year":"2006","unstructured":"Nash\u00a0P. 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