{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,25]],"date-time":"2023-11-25T11:42:04Z","timestamp":1700912524106},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"7-8","license":[{"start":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T00:00:00Z","timestamp":1659916800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T00:00:00Z","timestamp":1659916800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e4tsklinikum des Saarlandes und Medizinische Fakult\u00e4t der Universit\u00e4t des Saarlandes"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Wien Med Wochenschr"],"published-print":{"date-parts":[[2023,5]]},"abstract":"Summary<\/jats:title>Background and objective<\/jats:title>Umbilical venous catheters (UVC) and peripherally inserted central catheters (PICC) are commonly used in preterm infants but have been associated with a\u00a0number of serious complications. We performed a\u00a0survey in Austria and Germany to assess the use of UVCs and PICCs in preterm infants with a\u00a0birth weight <\u202f1250\u202fg and associated rates of catheter-related adverse events.<\/jats:p><\/jats:sec>Methods<\/jats:title>Electronic survey of participating centers of the NeoVitaA trial. Main outcome parameter was the reported rates of UVC- and PICC-associated complications (infection, thrombosis, emboli, organ injury, arrhythmia, dislocation, miscellaneous).<\/jats:p><\/jats:sec>Results<\/jats:title>In total, 20\u00a0neonatal intensive care units (NICU) providing maximal intensive care in Austria and Germany (level\u00a0I) were contacted, with a\u00a0senior neonatologist response rate of 12\/20 (60%). The reported rates for UVC with a\u00a0dwell time of 1\u201310\u00a0days were bacterial infection: 4.2\u202f\u00b1\u20093.4% (range 0\u201310%); thrombosis: 7.3\u202f\u00b1\u20097.1% (0\u201320%); emboli: 0.9\u202f\u00b1\u20092.0% (0\u20135%); organ injury: 1.1\u202f\u00b1\u20091.9% (0\u20135%); cardiac arrhythmia: 2.2\u202f\u00b1\u20092.5% (0\u20135%); and dislocation: 5.4\u202f\u00b1\u20098.7% (0\u201330%); and for PICCs with a\u00a0dwell time of 1\u201314\u00a0days bacterial infection: 15.0\u202f\u00b1\u20093.4% (range 2.5\u201330%); thrombosis; 4.3\u202f\u00b1\u20093.5% (0\u201310%); emboli: 0.8\u202f\u00b1\u20091.6% (0\u20135%); organ injury: 1.5\u202f\u00b1\u20092.3% (0\u20135%); cardiac arrhythmia: 1.5\u202f\u00b1\u20092.3% (0\u20135%), and dislocation: 8.5\u202f\u00b1\u20094.6% (0\u201330%).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>The catheter-related complication rates reported in this survey differed between UVCs and PICCs and were higher than those reported in the literature. To generate more reliable data on this clinically important issue, we plan to perform a\u00a0large prospective multicenter randomized controlled trial investigating the non-inferiority of a\u00a0prolonged UVC dwell time (up to 10\u00a0days) against the early change (up to 5\u00a0days) to a\u00a0PICC.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s10354-022-00952-z","type":"journal-article","created":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T09:03:18Z","timestamp":1659949398000},"page":"161-167","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Umbilical venous catheter- and peripherally inserted central catheter-associated complications in preterm infants with birth weight <\u202f1250\u00a0g","Nabelvenenkatheter- und periphere zentrale katheterassoziierte Komplikationen bei Fr\u00fchgeborenen mit einem Geburtsgewicht <\u202f1250\u00a0g"],"prefix":"10.1007","volume":"173","author":[{"given":"Steffi","family":"Hess","sequence":"first","affiliation":[]},{"given":"Martin","family":"Poryo","sequence":"additional","affiliation":[]},{"given":"Ralf","family":"B\u00f6ttger","sequence":"additional","affiliation":[]},{"given":"Axel","family":"Franz","sequence":"additional","affiliation":[]},{"given":"Daniel","family":"Klotz","sequence":"additional","affiliation":[]},{"given":"Knud","family":"Linnemann","sequence":"additional","affiliation":[]},{"given":"Torsten","family":"Ott","sequence":"additional","affiliation":[]},{"given":"Johannes","family":"P\u00f6schl","sequence":"additional","affiliation":[]},{"given":"Michael","family":"Schroth","sequence":"additional","affiliation":[]},{"given":"Anja","family":"Stein","sequence":"additional","affiliation":[]},{"given":"Elisabeth","family":"Ralser","sequence":"additional","affiliation":[]},{"given":"Heiko","family":"Reutter","sequence":"additional","affiliation":[]},{"given":"Ulrich H.","family":"Thome","sequence":"additional","affiliation":[]},{"given":"Christian","family":"Wieg","sequence":"additional","affiliation":[]},{"given":"Anne","family":"Ehrlich","sequence":"additional","affiliation":[]},{"given":"Christian","family":"Ruckes","sequence":"additional","affiliation":[]},{"given":"Stefan","family":"Wagenpfeil","sequence":"additional","affiliation":[]},{"given":"Michael","family":"Zemlin","sequence":"additional","affiliation":[]},{"given":"Cihan","family":"Papan","sequence":"additional","affiliation":[]},{"given":"Arne","family":"Simon","sequence":"additional","affiliation":[]},{"given":"Johannes","family":"Bay","sequence":"additional","affiliation":[]},{"ORCID":"http:\/\/orcid.org\/0000-0001-6016-4558","authenticated-orcid":false,"given":"Sascha","family":"Meyer","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2022,8,8]]},"reference":[{"key":"952_CR1","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1097\/00129804-200611000-00005","volume":"29","author":"P Nash","year":"2006","unstructured":"Nash\u00a0P. Umbilical catheters, placement, and complication management. J\u00a0Infus Nurs. 2006;29:346\u201352.","journal-title":"J Infus Nurs"},{"issue":"3","key":"952_CR2","doi-asserted-by":"publisher","first-page":"224","DOI":"10.3349\/ymj.1992.33.3.224","volume":"33","author":"GR Pereira","year":"1992","unstructured":"Pereira\u00a0GR, Lim\u00a0BK, Ing\u00a0C, et\u00a0al. Umbilical vs peripheral vein catheterization for parenteral nutrition in sick premature neonates. Yonsei Med\u00a0J. 1992;33(3):224\u201331.","journal-title":"Yonsei Med J"},{"key":"952_CR3","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1001\/jama.300.1.60","volume":"300","author":"R Carbajal","year":"2008","unstructured":"Carbajal\u00a0R, Rousset\u00a0A, Danan\u00a0C, et\u00a0al. Epidemiology and treatment of painful procedures in neonates in intensive care units. JAMA. 2008;300:60\u201370.","journal-title":"JAMA"},{"issue":"23","key":"952_CR4","doi-asserted-by":"publisher","first-page":"2612","DOI":"10.1001\/jama.2016.7020","volume":"315","author":"BS Ainsworth","year":"2016","unstructured":"Ainsworth\u00a0BS, McGuire\u00a0W. Peripherally inserted central catheters vs peripheral cannulas for delivering parenteral nutrition in neonates. JAMA. 2016;315(23):2612\u20133.","journal-title":"JAMA"},{"key":"952_CR5","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.clp.2004.11.005","volume":"32","author":"MC Hermansen","year":"2005","unstructured":"Hermansen\u00a0MC, Hermansen\u00a0MG. Intravascular catheter complications in the NICU. Clin Perinatol. 2005;32:141\u201356.","journal-title":"Clin Perinatol"},{"key":"952_CR6","doi-asserted-by":"publisher","first-page":"E91","DOI":"10.1111\/j.1440-1754.2010.01934.x","volume":"48","author":"J Wu","year":"2012","unstructured":"Wu\u00a0J, Mu\u00a0D. Vascular catheter-related complications in newborns. J\u00a0Paediatr Child Health. 2012;48:E91\u2013E5.","journal-title":"J Paediatr Child Health"},{"issue":"8","key":"952_CR7","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1111\/jpc.12690","volume":"50","author":"A Keir","year":"2014","unstructured":"Keir\u00a0A, Giesinger\u00a0R, Dunn\u00a0M. How long should umbilical venous catheters remain in place in neonates who require long-term (\u22655\u20137\u00a0days) central venous access? J\u00a0Paediatr Child Health. 2014;50(8):649\u201352.","journal-title":"J Paediatr Child Health"},{"issue":"9","key":"952_CR8","doi-asserted-by":"publisher","first-page":"e162","DOI":"10.1093\/cid\/cir257","volume":"52","author":"NP O\u2019Grady","year":"2011","unstructured":"Healthcare Infection Control Practices Advisory Committee (HICPAC), O\u2019Grady\u00a0NP, Alexander\u00a0M, Burns\u00a0LA, et al. Guidelines for the prevention of intravascular catheter-related infections. Clin Infect Dis. 2011;52(9):e162\u2013e93.","journal-title":"Clin Infect Dis"},{"issue":"3","key":"952_CR9","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1542\/peds.2010-2873","volume":"127","author":"J Schulman","year":"2011","unstructured":"New York State Regional Perinatal Care Centers, Schulman\u00a0J, Stricof\u00a0R, Stevens\u00a0TP, et al. Statewide NICU central-line-associated bloodstream infection rates decline after bundles and checklists. Pediatrics. 2011;127(3):436\u201344.","journal-title":"Pediatrics"},{"issue":"1","key":"952_CR10","doi-asserted-by":"publisher","first-page":"e25","DOI":"10.1542\/peds.2005-1880","volume":"118","author":"M Butler-O\u2019Hara","year":"2006","unstructured":"Butler-O\u2019Hara\u00a0M, Buzzard\u00a0CJ, Reubens\u00a0L, et al. A randomized trial comparing long-term and short-term use of umbilical venous catheters in premature infants with birth weights of less than 1251 grams. Pediatrics. 2006;118(1):e25\u2013e35.","journal-title":"Pediatrics"},{"issue":"5","key":"952_CR11","doi-asserted-by":"publisher","first-page":"1314","DOI":"10.1542\/peds.2008-0656","volume":"123","author":"MM Lahra","year":"2009","unstructured":"Lahra\u00a0MM, Beeby\u00a0PJ, Jeffery\u00a0HE. Intrauterine inflammation, neonatal sepsis, and chronic lung disease: a\u00a013-year hospital cohort study. Pediatrics. 2009;123(5):1314\u20139.","journal-title":"Pediatrics"},{"issue":"19","key":"952_CR12","doi-asserted-by":"publisher","first-page":"2357","DOI":"10.1001\/jama.292.19.2357","volume":"292","author":"BJ Stoll","year":"2004","unstructured":"National Institute of Child Health and Human Development Neonatal Research Network, Stoll\u00a0BJ, Hansen\u00a0NI, Adams-Chapman\u00a0I, et al. Neurodevelopmental and growth impairment among extremely lowbirth-weight infants with neonatal infection. JAMA. 2004;292(19):2357\u201365.","journal-title":"JAMA"},{"issue":"2","key":"952_CR13","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1016\/j.jpeds.2008.02.033","volume":"153","author":"DK Shah","year":"2008","unstructured":"Shah\u00a0DK, Doyle\u00a0LW, Anderson\u00a0PJ, et\u00a0al. Adverse neurodevelopment in preterm infants with postnatal sepsis or necrotizing enterocolitis is mediated by white matter abnormalities on magnetic resonance imaging at term. J\u00a0Pediatr. 2008;153(2):170\u20135.","journal-title":"J Pediatr"},{"issue":"1","key":"952_CR14","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1542\/peds.2008-0377","volume":"123","author":"D Bassler","year":"2009","unstructured":"Trial of Indomethacin Prophylaxis in Preterms Investigators, Bassler\u00a0D, Stoll\u00a0BJ, Schmidt\u00a0B, et\u00a0al. Using a\u00a0count of neonatal morbidities to predict poor outcome in extremely low birth weight infants: added role of neonatal infection. Pediatrics. 2009;123(1):313\u20138.","journal-title":"Pediatrics"},{"key":"952_CR15","doi-asserted-by":"publisher","first-page":"w13954","DOI":"10.4414\/smw.2014.13954","volume":"144","author":"SB R\u00f6hr","year":"2014","unstructured":"R\u00f6hr\u00a0SB, Sauer\u00a0H, Gottschling\u00a0S, et al. Non-neurological, steroid-related adverse events in very low birth weight infants: a prospective audit. Swiss Med Wkly. 2014;144:w13954. https:\/\/doi.org\/10.4414\/smw.2014.13954.","journal-title":"Swiss Med Wkly"},{"issue":"17","key":"952_CR16","doi-asserted-by":"crossref","first-page":"2817","DOI":"10.3109\/14767058.2015.1105952","volume":"29","author":"M Mutlu","year":"2016","unstructured":"Mutlu\u00a0M, Aslan\u00a0Y, Kul\u00a0S, et al. Umbilical venous catheter complications in newborns: a\u00a06-year single-center experience. J\u00a0Matern Fetal Neonatal Med. 2016;29(17):2817\u201322.","journal-title":"J Matern Fetal Neonatal Med"},{"issue":"3","key":"952_CR17","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1159\/000494369","volume":"115","author":"GHM Dubbink-Verheij","year":"2019","unstructured":"Dubbink-Verheij\u00a0GHM, Visser\u00a0R, Tan\u00a0RNGB, et al. Inadvertent migration of umbilical venous catheters often leads to malposition. Neonatology. 2019;115(3):205\u201310.","journal-title":"Neonatology"},{"issue":"6","key":"952_CR18","doi-asserted-by":"publisher","first-page":"972","DOI":"10.1016\/j.jpeds.2011.12.004","volume":"160","author":"M Butler-O\u2019Hara","year":"2012","unstructured":"Butler-O\u2019Hara\u00a0M, D\u2019Angio\u00a0CT, Hoey\u00a0H, et al. An evidence-based catheter bundle alters central venous catheter strategy in newborn infants. J\u00a0Pediatr. 2012;160(6):972\u2013977.e2.","journal-title":"J Pediatr"},{"issue":"5","key":"952_CR19","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1001\/jamapediatrics.2013.775","volume":"167","author":"K Jumani","year":"2013","unstructured":"Jumani\u00a0K, Advani\u00a0S, Reich\u00a0NG, et\u00a0al. Risk factors for peripherally inserted central venous catheter complications in children. JAMA Pediatr. 2013;167(5):429\u201335.","journal-title":"JAMA Pediatr"},{"issue":"6 Pt B","key":"952_CR20","doi-asserted-by":"publisher","first-page":"2379","DOI":"10.1016\/j.clnu.2018.06.952","volume":"37","author":"S Kola\u010dek","year":"2018","unstructured":"Kola\u010dek\u00a0S, Puntis\u00a0JWL, Hojsak\u00a0I, ESPGHAN\/ESPEN\/ESPR\/CSPEN working group on pediatric parenteral nutrition. ESPGHAN\/ESPEN\/ESPR\/CSPEN guidelines on pediatric parenteral nutrition: Venous access. Clin Nutr. 2018;37(6 Pt B):2379\u201391.","journal-title":"Clin Nutr"},{"key":"952_CR21","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1016\/S0095-5108(05)70026-9","volume":"27","author":"MF Whitfield","year":"2000","unstructured":"Whitfield\u00a0MF, Grunau\u00a0RE. Behavior, pain perception, and the extremely low-birth weight survivor. Clin Perinatol. 2000;27:363\u201379.","journal-title":"Clin Perinatol"},{"issue":"3","key":"952_CR22","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1159\/000357212","volume":"105","author":"S Meyer","year":"2014","unstructured":"Meyer\u00a0S, Gortner\u00a0L, NeoVitaA Trial Investigators. Early postnatal additional high-dose oral vitamin A supplementation versus placebo for 28 days for preventing bronchopulmonary dysplasia or death in extremely low birth weight infants. Neonatology. 2014;105(3):182\u20138.","journal-title":"Neonatology"},{"key":"952_CR23","unstructured":"National Healthcare Safety Network DoHQP. Centers for Disease Control and Prevention: CDC\/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. 2022. http:\/\/www.cdc.gov\/ncidod\/dhqp\/pdf\/nnis\/NosInfDefinitions.pdf."},{"key":"952_CR24","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1016\/j.jhin.2008.01.016","volume":"68","author":"C Geffers","year":"2008","unstructured":"Geffers\u00a0C, Baerwolff\u00a0S, Schwab\u00a0F, et al. Incidence of healthcare-associated infections in high-risk neonates: results from the German surveillance system for very-low-birthweight infants. J\u00a0Hosp Infect. 2008;68:214\u201321.","journal-title":"J Hosp Infect"},{"issue":"10","key":"952_CR25","doi-asserted-by":"publisher","first-page":"2505","DOI":"10.1038\/s41372-021-01147-x","volume":"41","author":"K Gibson","year":"2021","unstructured":"Gibson\u00a0K, Sharp\u00a0R, Ullman\u00a0A, et al. Adverse events associated with umbilical catheters: a systematic review and meta-analysis. J\u00a0Perinatol. 2021;41(10):2505\u201312.","journal-title":"J Perinatol"},{"key":"952_CR26","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1038\/s41372-019-0579-3","volume":"40","author":"OL Levit","year":"2020","unstructured":"Levit\u00a0OL, Shabanova\u00a0V, Bizzarro\u00a0MJ. Umbilical catheter-associated complications in a\u00a0level IV neonatal intensive care unit. J\u00a0Perinatol. 2020;40:573\u201380.","journal-title":"J Perinatol"},{"key":"952_CR27","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1136\/archdischild-2018-316762","volume":"105","author":"GH Dubbink-Verheij","year":"2020","unstructured":"Dubbink-Verheij\u00a0GH, Visser\u00a0R, Roest\u00a0AA, et al. Thrombosis after umbilical venous catheter: prospective study with serial ultrasound. Arch Dis Child Fetal Neonatal Ed. 2020;105:299\u2013303.","journal-title":"Arch. Dis. Child. Fetal Neonatal Ed."},{"key":"952_CR28","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1038\/s41372-019-0575-7","volume":"40","author":"GC Pet","year":"2020","unstructured":"Pet\u00a0GC, Eickhoff\u00a0JC, McNevin\u00a0KE, et\u00a0al. Risk factors for peripherally inserted central catheter complications in neonates. J\u00a0Perinatol. 2020;40:581\u20138.","journal-title":"J Perinatol"},{"key":"952_CR29","doi-asserted-by":"publisher","author":"M Poryo","year":"2022","unstructured":"Poryo\u00a0M, Hess\u00a0S, Stock\u00a0L, Ruffing\u00a0S, et\u00a0al. Myocardial ischemia in a preterm born baby. Klin Padiatr. 2022; https:\/\/doi.org\/10.1055\/a-1765-7203.","journal-title":"Klin Padiatr","DOI":"10.1055\/a-1765-7203"},{"issue":"3","key":"952_CR30","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1055\/s-0037-1606607","volume":"35","author":"S Mohamed","year":"2018","unstructured":"Canadian Neonatal Network Investigators, Mohamed\u00a0S, Elboraee\u00a0JT, Xiang\u00a0YY, et\u00a0al. Association between umbilical catheters and neonatal outcomes in extremely preterm infants. Am J Perinatol. 2018;35(3):233\u201341.","journal-title":"Am J Perinatol"},{"key":"952_CR31","doi-asserted-by":"publisher","author":"A Simon","year":"2021","unstructured":"Simon\u00a0A, Zemlin\u00a0M, Geipel\u00a0M, et\u00a0al. Infection prevention in neonatal intensive care units. Gyn\u00e4kologe. 2021; https:\/\/doi.org\/10.1007\/s00129-021-04804-6.","journal-title":"Gyn\u00e4kologe","DOI":"10.1007\/s00129-021-04804-6"}],"container-title":["Wiener Medizinische Wochenschrift"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10354-022-00952-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10354-022-00952-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10354-022-00952-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,25]],"date-time":"2023-11-25T11:24:40Z","timestamp":1700911480000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10354-022-00952-z"}},"subtitle":["Results from a\u00a0survey in Austria and Germany","Ergebnisse einer Umfrage in \u00d6sterreich und Deutschland"],"short-title":[],"issued":{"date-parts":[[2022,8,8]]},"references-count":31,"journal-issue":{"issue":"7-8","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["952"],"URL":"http:\/\/dx.doi.org\/10.1007\/s10354-022-00952-z","relation":{},"ISSN":["0043-5341","1563-258X"],"issn-type":[{"value":"0043-5341","type":"print"},{"value":"1563-258X","type":"electronic"}],"subject":["General Medicine"],"published":{"date-parts":[[2022,8,8]]},"assertion":[{"value":"12 May 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 June 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 August 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"S.\u00a0Hess, M.\u00a0Poryo, R.\u00a0B\u00f6ttger, A.\u00a0Franz, D.\u00a0Klotz, K.\u00a0Linnemann, T.\u00a0Ott, J.\u00a0P\u00f6schl, M.\u00a0Schroth, A.\u00a0Stein, E.\u00a0Ralser, H.\u00a0Reutter, U.\u00a0H.\u00a0Thome, C.\u00a0Wieg, A.\u00a0Ehrlich, C.\u00a0Ruckes, S.\u00a0Wagenpfeil,M.\u00a0Zemlin, C.\u00a0Papan, A.\u00a0Simon, J.\u00a0Bay, and S.\u00a0Meyer declare that they have no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}