1 line
24 KiB
Plaintext
1 line
24 KiB
Plaintext
{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,4,13]],"date-time":"2023-04-13T04:48:29Z","timestamp":1681361309416},"reference-count":65,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klinische Neurophysiologie"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Bei der Amyotrophen Lateralsklerose (ALS) handelt sich um eine neurodegenerative\n Multisystemerkrankung. Diese \u00e4u\u00dfert sich neben den motorischen\n Defiziten mit nicht-motorischen Symptomen. Hierzu z\u00e4hlen auch autonome\n St\u00f6rungen, die von ver\u00e4nderter Schwei\u00dfsekretion\n \u00fcber Tachykardie bis zu gastrointestinalen Symptomen reichen. Autonome\n St\u00f6rungen k\u00f6nnen mit verschiedenen Methoden, wie\n Selbsterhebungsfrageb\u00f6gen, Messung der Herzfrequenzvariabilit\u00e4t,\n QTc-Intervallmessung, Erhebung der sudomotorischen Funktion und Sonographie des\n Nervus vagus erfasst werden, die in diesem Artikel dargestellt werden. Die\n bislang bei der ALS eingesetzten Methoden der autonomen Diagnostik ergeben zum\n Teil deutlich divergierende Ergebnisse \u00fcber die Aktivit\u00e4t des\n Sympathikus im Krankheitsverlauf. Relevante autonome St\u00f6rungen scheinen\n zumeist erst im fortgeschrittenen Krankheitsstadium aufzutreten, wobei\n multizentrische Studien mit longitudinalem Ansatz ausstehen.<\/jats:p>","DOI":"10.1055\/a-2018-3174","type":"journal-article","created":{"date-parts":[[2023,3,14]],"date-time":"2023-03-14T23:39:25Z","timestamp":1678837165000},"page":"22-27","source":"Crossref","is-referenced-by-count":0,"title":["Autonome Diagnostik bei der Amyotrophen\n Lateralsklerose"],"prefix":"10.1055","volume":"54","author":[{"given":"Moritz","family":"Metelmann","sequence":"additional","affiliation":[{"name":"Department of Neurology,Universit\u00e4tsklinikum Leipzig, Leipzig,\n Germany"}]},{"given":"Petra","family":"Baum","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Neurologie , Universit\u00e4tsklinikum Leipzig,\n Leipzig, Germany"}]},{"given":"Johann","family":"Pelz","sequence":"additional","affiliation":[{"name":"Department of Neurology,Universit\u00e4tsklinikum Leipzig, Leipzig,\n Germany"}]}],"member":"194","published-online":{"date-parts":[[2023,3,14]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"117","DOI":"10.3389\/fneur.2016.00117","article-title":"Non-Motor Symptoms in Patients Suffering from Motor Neuron Diseases","volume":"7","author":"R G\u00fcnther","year":"2016","journal-title":"Front Neurol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1097\/01.wco.0000183114.76056.0e","article-title":"Autonomic impairment in amyotrophic lateral sclerosis","volume":"18","author":"R Baltadzhieva","year":"2005","journal-title":"Curr Opin Neurol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"46","DOI":"10.17925\/ENR.2013.08.01.46","article-title":"Sympathetic Hyperactivity and Sympathovagal Imbalance in Amyotrophic Lateral\n Sclerosis","volume":"8","author":"T. Shimizu","year":"2012","journal-title":"European Neurological Review"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/0022-510x(94)90009-4","article-title":"Circulatory collapse and sudden death in respirator-dependent amyotrophic\n lateral sclerosis","volume":"124","author":"T Shimizu","year":"1994","journal-title":"Journal of the Neurological Sciences"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1007\/s00415-021-10651-1","article-title":"A systematic review of non-motor symptom evaluation in clinical trials for\n amyotrophic lateral sclerosis","volume":"269","author":"E Beswick","year":"2022","journal-title":"J Neurol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"748","DOI":"10.1016\/s0025-6196(12)60631-4","article-title":"Composite Autonomic Scoring Scale for Laboratory Quantification of Generalized\n Autonomic Failure","volume":"68","author":"PA. Low","year":"1993","journal-title":"Mayo Clinic Proceedings"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1002\/mus.24457","article-title":"Autonomic system and amyotrophic lateral sclerosis","volume":"51","author":"E A Piccione","year":"2015","journal-title":"Muscle Nerve"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1212\/wnl.52.3.523","article-title":"The Autonomic Symptom Profile: a new instrument to assess autonomic\n symptoms","volume":"52","author":"G A Suarez","year":"1999","journal-title":"Neurology"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"1196","DOI":"10.1016\/j.mayocp.2012.10.013","article-title":"COMPASS 31: a refined and abbreviated Composite Autonomic Symptom Score","volume":"87","author":"D M Sletten","year":"2012","journal-title":"Mayo Clinic Proceedings"},{"key":"ref10","doi-asserted-by":"publisher","article-title":"Stereological and electrophysiological evaluation of autonomic involvement in\n amyotrophic lateral sclerosis","author":"R Ozturk","year":"2022","journal-title":"Neurophysiol Clin","DOI":"10.1016\/j.neucli.2022.08.003"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1111\/jon.12993","article-title":"Autonomic dysfunction in amyotrophic lateral sclerosis: A neurophysiological and\n neurosonology study","volume":"32","author":"M Papadopoulou","year":"2022","journal-title":"J Neuroimaging"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1111\/ene.15177","article-title":"Multimodal assessment of autonomic dysfunction in amyotrophic lateral\n sclerosis","volume":"29","author":"D Weise","year":"2022","journal-title":"Eur J Neurol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"e14536","DOI":"10.1111\/ijcp.14536","article-title":"The importance of heart rate variability in predicting cardiac autonomic\n dysfunction in patients with amyotrophic lateral sclerosis","volume":"75","author":"D \u0130\u015fcan","year":"2021","journal-title":"Int J Clin Pract"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1111\/neup.12303","article-title":"A Japanese familial ALS patient with autonomic failure and a p.Cys146Arg\n mutation in the gene for SOD1 (SOD1 )","volume":"36","author":"K Hayashi","year":"2016","journal-title":"Neuropathology"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1111\/neup.12057","article-title":"Concomitant alpha-synuclein pathology in an autopsy case of amyotrophic lateral\n sclerosis presenting with orthostatic hypotension and cardiac arrests","volume":"34","author":"T Yamada","year":"2014","journal-title":"Neuropathology"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1088","DOI":"10.4187\/respcare.06681","article-title":"Decreased Heart Rate Variability in Individuals With Amyotrophic Lateral\n Sclerosis","volume":"64","author":"RM M Pimentel","year":"2019","journal-title":"Respir Care"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1161\/01.CIR.93.5.1043","article-title":"Heart Rate Variability","volume":"93","author":"Electrophysiology TFotESoCtNA","year":"1996","journal-title":"Circulation"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"272","DOI":"10.3109\/17482960903390855","article-title":"Impairment of cardiac autonomic control in patients with amyotrophic lateral\n sclerosis","volume":"11","author":"S Pavlovic","year":"2010","journal-title":"Amyotroph Lateral Scler"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"363","DOI":"10.3109\/17482968.2011.584628","article-title":"Autonomic dysfunction in the early stage of ALS with bulbar involvement","volume":"12","author":"A Merico","year":"2011","journal-title":"Amyotroph Lateral Scler"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1002\/mus.23313","article-title":"Decreased heart rate variability predicts death in amyotrophic lateral\n sclerosis","volume":"46","author":"S Pinto","year":"2012","journal-title":"Muscle Nerve"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"B4","DOI":"10.1016\/0002-9149(93)90032-8","article-title":"Mechanisms and models to predict a QTc effect","volume":"72","author":"E. Moore","year":"1993","journal-title":"The American Journal of Cardiology"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"2096","DOI":"10.1111\/j.1540-8159.1990.tb06949.x","article-title":"Heart rate variability and sudden infant death syndrome","volume":"13","author":"F Perticone","year":"1990","journal-title":"Pacing Clin Electrophysiol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.jns.2007.01.007","article-title":"Sympathetic disturbances increase risk of sudden cardiac arrest in sporadic\n ALS","volume":"254","author":"H Asai","year":"2007","journal-title":"Journal of the Neurological Sciences"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"479","DOI":"10.3389\/fneur.2017.00479","article-title":"Cardiac Findings in Amyotrophic Lateral Sclerosis: A Magnetic Resonance Imaging\n Study","volume":"8","author":"A Rosenbohm","year":"2017","journal-title":"Front Neurol"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"1799","DOI":"10.1007\/s12350-020-02501-w","article-title":"The prognostic value of 123I-mIBG SPECT cardiac imaging in heart failure\n patients: a systematic review","volume":"29","author":"M Pontico","year":"2022","journal-title":"J Nucl Cardiol"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"25S","DOI":"10.2967\/jnumed.115.157503","article-title":"123I-MIBG SPECT for Evaluation of Patients with Heart Failure","volume":"56","author":"A C Dimitriu-Leen","year":"2015","journal-title":"J Nucl Med"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1111\/j.1600-0404.1999.tb00681.x","article-title":"Cardiac sympathetic denervation in early stages of amyotrophic lateral sclerosis\n demonstrated by 123I-MIBG-SPECT","volume":"99","author":"A Druschky","year":"1999","journal-title":"Acta Neurol Scand"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1016\/j.parkreldis.2012.10.011","article-title":"Lewy pathology in an autopsy case of FTLD-MND with reduced cardiac MIBG uptake\n and depletion of cardiac sympathetic fibers","volume":"19","author":"N Nomoto","year":"2013","journal-title":"Parkinsonism Relat Disord"},{"key":"ref29","first-page":"341","article-title":"A case of familial amyotrophic lateral sclerosis with markedly decreased\n accumulation on 123I-MIBG myocardiac scintigraphy and atonic bladder","volume":"36","author":"T Yamamoto","year":"1996","journal-title":"Rinsho Shinkeigaku"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"2380","DOI":"10.1007\/s00415-013-7005-0","article-title":"Cardiac sympathetic function in the patients with amyotrophic lateral sclerosis:\n analysis using cardiac 123I MIBG scintigraphy","volume":"260","author":"Y Tanaka","year":"2013","journal-title":"J Neurol"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1136\/jnnp.73.1.68","article-title":"Progressive sudomotor dysfunction in amyotrophic lateral sclerosis","volume":"73","author":"M Beck","year":"2002","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1136\/jnnp.72.3.356","article-title":"Organisation of the sympathetic skin response in spinal cord injury","volume":"72","author":"P Cariga","year":"2002","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1136\/jnnp.47.5.536","article-title":"Sympathetic skin response \u2013 a method of assessing unmyelinated axon\n dysfunction in peripheral neuropathies","volume":"47","author":"B T Shahani","year":"1984","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.neulab.2018.03.001","article-title":"Neurophysiologische Diagnostik des autonomen Nervensystems","volume":"40","author":"P. Baum","year":"2018","journal-title":"Das Neurophysiologie-Labor"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"e6523","DOI":"10.1097\/MD.0000000000006523","article-title":"Sympathetic skin response and heart rate variability in predicting autonomic\n disorders in patients with Parkinson disease","volume":"96","author":"J-Q Ke","year":"2017","journal-title":"Medicine (Baltimore)"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"2032","DOI":"10.1016\/j.clinph.2021.05.016","article-title":"Assessment of sympathetic sudomotor function in amyotrophic lateral sclerosis\n with electrochemical skin conductance","volume":"132","author":"M Oliveira Santos","year":"2021","journal-title":"Clin Neurophysiol"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1002\/mus.21464","article-title":"Relationship of Q-sweat to quantitative sudomotor axon reflex test (QSART)\n volumes","volume":"41","author":"D M Sletten","year":"2010","journal-title":"Muscle Nerve"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1016\/j.tcm.2017.05.003","article-title":"Recording sympathetic nerve activity from the skin","volume":"27","author":"T H Everett","year":"2017","journal-title":"Trends Cardiovasc Med"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1016\/j.jfma.2020.07.025","article-title":"Complex dynamics of skin sympathetic nerve activities as a prognostic predictor\n for critically ill patients","volume":"120","author":"J-J Chen","year":"2021","journal-title":"J Formos Med Assoc"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1111\/j.1748-1716.1972.tb05167.x","article-title":"General characteristics of sympathetic activity in human skin nerves","volume":"84","author":"K E Hagbarth","year":"1972","journal-title":"Acta Physiol Scand"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"39","DOI":"10.3109\/17482968.2010.508529","article-title":"Sympathetic sudomotor neural function in amyotrophic lateral sclerosis","volume":"12","author":"K Shindo","year":"2011","journal-title":"Amyotroph Lateral Scler"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"117543","DOI":"10.1016\/j.jns.2021.117543","article-title":"Bowel, bladder, and sudomotor symptoms in ALS patients","volume":"427","author":"V C Samara","year":"2021","journal-title":"Journal of the Neurological Sciences"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"e249","DOI":"10.1016\/j.rehab.2018.05.580","article-title":"Correlation between sudomotor dysfunction and functional status in patients with\n amyotrophic lateral sclerosis","volume":"61","author":"S Y Kim","year":"2018","journal-title":"Annals of Physical and Rehabilitation Medicine"},{"key":"ref44","first-page":"193","article-title":"Sudomotor dysfunction in amyotrophic lateral sclerosis","volume":"9","author":"M Kihara","year":"1994","journal-title":"Funct Neurol"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1080\/146608201316949550","article-title":"Sympathetic sudomotor function and amyotrophic lateral sclerosis","volume":"2","author":"M Santos-Bento","year":"2001","journal-title":"Amyotroph Lateral Scler Other Motor Neuron Disord"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.neulab.2019.03.001","article-title":"Sonographie des N. vagus \u2013 Methodik und Indikation","volume":"41","author":"J Pelz","year":"2019","journal-title":"Das Neurophysiologie-Labor"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1002\/mus.25993","article-title":"Sonographic evaluation of the vagus nerves: Protocol, reference values, and\n side-to-side differences","volume":"57","author":"J O Pelz","year":"2018","journal-title":"Muscle Nerve"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"1657","DOI":"10.1016\/j.clinph.2015.06.032","article-title":"Ultrasound and electrophysiologic findings in patients with\n Guillain-Barr\u00e9 syndrome at disease onset and over a period of six\n months","volume":"127","author":"A Grimm","year":"2016","journal-title":"Clin Neurophysiol"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"102552","DOI":"10.1016\/j.autneu.2019.05.004","article-title":"Correlation between sonographic morphology and function of the cervical vagus\n nerves","volume":"220","author":"J O Pelz","year":"2019","journal-title":"Auton Neurosci"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"951","DOI":"10.3389\/fneur.2018.00951","article-title":"Axonal Degeneration of the Vagus Nerve in Parkinson's Disease-A\n High-Resolution Ultrasound Study","volume":"9","author":"J O Pelz","year":"2018","journal-title":"Front Neurol"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1016\/j.parkreldis.2018.06.002","article-title":"The vagus nerve becomes smaller in patients with Parkinson's disease: A\n preliminary cross-sectional study using ultrasonography","volume":"55","author":"K Tsukita","year":"2018","journal-title":"Parkinsonism Relat Disord"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1111\/jon.12761","article-title":"Ultrasound Detection of Vagus Nerve Atrophy in Bulbar Amyotrophic Lateral\n Sclerosis","volume":"30","author":"K Holzapfel","year":"2020","journal-title":"J Neuroimaging"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1002\/mus.25126","article-title":"Vagus nerve ultrasound in a patient with amyotrophic lateral sclerosis","volume":"54","author":"EA. Tawfik","year":"2016","journal-title":"Muscle Nerve"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1080\/146608299300079484","article-title":"Gastrointestinal dysfunction in amyotrophic lateral sclerosis","volume":"1","author":"M Toepfer","year":"1999","journal-title":"Amyotroph Lateral Scler Other Motor Neuron Disord"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1159\/000517613","article-title":"Prevalence of Gastrointestinal Symptoms, Severity of Dysphagia, and Their\n Correlation with Severity of Amyotrophic Lateral Sclerosis in a Mexican\n Cohort","volume":"21","author":"C Parra-Cantu","year":"2021","journal-title":"Neurodegener Dis"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"174","DOI":"10.3109\/21678421.2013.868001","article-title":"Increased prevalence of bladder and intestinal dysfunction in amyotrophic\n lateral sclerosis","volume":"15","author":"G S N\u00fcbling","year":"2014","journal-title":"Amyotroph Lateral Scler Frontotemporal Degener"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1002\/nau.22976","article-title":"Urodynamic findings in amyotrophic lateral sclerosis patients with lower urinary\n tract symptoms: Results from a pilot study","volume":"36","author":"S Arlandis","year":"2017","journal-title":"Neurourol Urodyn"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.jns.2017.04.053","article-title":"Clinical profile of motor neuron disease patients with lower urinary tract\n symptoms and neurogenic bladder","volume":"378","author":"J F V\u00e1zquez-Costa","year":"2017","journal-title":"Journal of the Neurological Sciences"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/S1566-0702(01)00217-X","article-title":"Effect of tamsulosin hydrochloride on sympathetic hyperactivity in amyotrophic\n lateral sclerosis","volume":"88","author":"T Ohno","year":"2001","journal-title":"Autonomic Neuroscience"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1007\/BF02291141","article-title":"Amyotrophic lateral sclerosis with hypertensive attacks: blood pressure changes\n in response to drug administration","volume":"6","author":"T Shimizu","year":"1996","journal-title":"Clin Auton Res"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1007\/bf01826200","article-title":"Hyposensitivity of peripheral \u03b1-adrenoceptors in respiratordependent\n amyotrophic lateral sclerosis assessed by intravenous norepinephrine\n infusion","volume":"5","author":"T Shimizu","year":"1995","journal-title":"Clin Auton Res"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"2310","DOI":"10.1152\/jappl.1993.75.5.2310","article-title":"Important influence of respiration on human R-R interval power spectra is\n largely ignored","volume":"75","author":"T E Brown","year":"1993","journal-title":"J Appl Physiol (1985)"},{"key":"ref63","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/S0022-510X(03)00143-6","article-title":"Increased hypoxic blood pressure response in patients with amyotrophic lateral\n sclerosis","volume":"213","author":"M J Hecht","year":"2003","journal-title":"Journal of the Neurological Sciences"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"241","DOI":"10.5692\/clinicalneurol.cn-000837","article-title":"Tracheostomy and invasive mechanical ventilation in amyotrophic lateral\n sclerosis: decision-making factors and survival analysis","volume":"56","author":"F. Kimura","year":"2016","journal-title":"Rinsho Shinkeigaku"},{"key":"ref65","doi-asserted-by":"publisher","first-page":"1160","DOI":"10.1111\/ene.14647","article-title":"Non-invasive and tracheostomy invasive ventilation in amyotrophic lateral\n sclerosis: Utilization and survival rates in a cohort study over 12 years in\n Germany","volume":"28","author":"S Spittel","year":"2021","journal-title":"Eur J Neurol"}],"container-title":["Klinische Neurophysiologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2018-3174.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,12]],"date-time":"2023-04-12T11:34:02Z","timestamp":1681299242000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2018-3174"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3]]},"references-count":65,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2023,3,14]]},"published-print":{"date-parts":[[2023,3]]}},"URL":"http:\/\/dx.doi.org\/10.1055\/a-2018-3174","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1434-0275","1439-4081"],"issn-type":[{"value":"1434-0275","type":"print"},{"value":"1439-4081","type":"electronic"}],"subject":["Physiology (medical)","Neurology (clinical)"],"published":{"date-parts":[[2023,3]]}}} |