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{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T13:11:20Z","timestamp":1696857080500},"reference-count":65,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2022,11,14]],"date-time":"2022-11-14T00:00:00Z","timestamp":1668384000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,11,14]],"date-time":"2022-11-14T00:00:00Z","timestamp":1668384000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100008678","name":"Universit\u00e4t Leipzig","doi-asserted-by":"crossref"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Radiol"],"abstract":"<jats:title>Abstract\n<\/jats:title><jats:p>Cystic fibrosis (CF) is one of the most common inherited and life-shortening pulmonary diseases in the Caucasian population. With the widespread introduction of newborn screening and the development of modulator therapy, tremendous advances have been made in recent years both in diagnosis and therapy. Since paediatric CF patients tend to be younger and have lower morbidity, the type of imaging modality that should be used to monitor the disease is often debated. Computed tomography (CT) is sensitive to many pulmonary pathologies, but radiation exposure limits its use, especially in children and adolescents. Conventional pulmonary magnetic\u00a0resonance imaging (MRI) is a valid alternative to CT and, in most cases, provides sufficient information to guide treatment. Given the expected widespread availability of sequences with ultra-short echo times, there will be even fewer reasons to perform CT for follow-up of patients with CF. This review aims to provide an overview of the process and results of monitoring CF with MRI, particularly for centres not specialising in the disease.<\/jats:p>","DOI":"10.1007\/s00247-022-05539-9","type":"journal-article","created":{"date-parts":[[2022,11,14]],"date-time":"2022-11-14T01:03:08Z","timestamp":1668387788000},"page":"640-648","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Chest magnetic resonance imaging in cystic fibrosis: technique and clinical benefits"],"prefix":"10.1007","volume":"53","author":[{"ORCID":"http:\/\/orcid.org\/0000-0002-7680-0990","authenticated-orcid":false,"given":"Daniel","family":"Gr\u00e4fe","sequence":"first","affiliation":[]},{"ORCID":"http:\/\/orcid.org\/0000-0002-2838-593X","authenticated-orcid":false,"given":"Freerk","family":"Prenzel","sequence":"additional","affiliation":[]},{"ORCID":"http:\/\/orcid.org\/0000-0003-0960-3740","authenticated-orcid":false,"given":"Franz Wolfgang","family":"Hirsch","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2022,11,14]]},"reference":[{"key":"5539_CR1","doi-asserted-by":"publisher","first-page":"589","DOI":"10.3390\/genes11060589","volume":"11","author":"V Scotet","year":"2020","unstructured":"Scotet V, L\u2019Hostis C, F\u00e9rec C (2020) The changing epidemiology of cystic fibrosis: Incidence, survival and impact of the CFTRGene discovery. Genes (Basel) 11:589","journal-title":"Genes (Basel)"},{"key":"5539_CR2","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1016\/j.jcf.2008.03.007","volume":"7","author":"PM Farrell","year":"2008","unstructured":"Farrell PM (2008) The prevalence of cystic fibrosis in the European Union. J Cyst Fibros 7:450\u2013453","journal-title":"J Cyst Fibros"},{"key":"5539_CR3","doi-asserted-by":"publisher","first-page":"2519","DOI":"10.1016\/S0140-6736(16)00576-6","volume":"388","author":"JS Elborn","year":"2016","unstructured":"Elborn JS (2016) Cystic fibrosis. Lancet 388:2519\u20132531","journal-title":"Lancet"},{"key":"5539_CR4","first-page":"3","volume":"42","author":"IM Balfour-Lynn","year":"2020","unstructure
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