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{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,19]],"date-time":"2024-01-19T08:16:51Z","timestamp":1705652211274},"reference-count":48,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T00:00:00Z","timestamp":1679875200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["beva.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Equine Veterinary Journal"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Osteochondral fragment removal is commonly performed but there are little scientific data supporting this procedure in the absence of clinical signs. More information is needed to facilitate clinical decision\u2010making regarding fragment removal of the metacarpo\u2212\/metatarsophalangeal joint.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To assess prevalence of cartilage injury in the equine metacarpo\u2212\/metatarsophalangeal joint and its association to fragment size, location, age and lameness.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Retrospective observational study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Clinical records, including radiographs of 823 metacarpo\u2212\/metatarsophalangeal joints (640 horses) that underwent arthroscopic fragment removal, were reviewed. Fragment size, intra\u2010articular fragment location and cartilage injury score were recorded. Presence of synovitis was retrospectively evaluated in 157 joints. Kruskal\u2013Wallis and Mann\u2013Whitney tests were used for group comparisons, and Dunn's post hoc test was applied for multiple comparisons. Linear regression analysis was used to assess strength of association between age and mean cartilage score. Univariable regression analysis was performed and variables with <jats:italic>p<\/jats:italic>\u2009<\u20090.2 were used in the final mixed\u2010effects multivariable model to which backwards stepwise selection was applied. Significance level was <jats:italic>p<\/jats:italic>\u2009<\u20090.05.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Cartilage injury was present in 28.8% (95% CI\u00a0=\u00a025.8\u201332.0) of joints. Lameness was not associated with fragment location or fragment size. Fragment size was not associated with cartilage injury. Age (OR\u00a0=\u00a01.35, 95% CI\u00a0=\u00a01.22\u20131.48, <jats:italic>p<\/jats:italic>\u2009<\u20090.001) and lameness (OR\u00a0=\u00a05.03, 95% CI\u00a0=\u00a02.27\u201311.68, <jats:italic>p<\/jats:italic>\u2009<\u20090.001) were associated with cartilage injury as well as fragment location (palmar\/plantar, OR\u00a0=\u00a00.22, 95% CI\u00a0=\u00a00.13\u20130.38, <jats:italic>p<\/jats:italic>\u2009<\u20090.001), with dorsal fragments being more likely to be associated with cartilage lesions than palmar\/plantar fragments. There was a significant association between age and mean cartilage score (<jats:italic>b<\/jats:italic>\u00a0=\u00a00.18, 95% CI\u00a0=\u00a00.14\u20130.22, <jats:italic>p<\/jats:italic>\u2009<\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Main limitations<\/jats:title><jats:p>The series included a heterogenous group of horses of different breed, sex, age and use. Data were collected retrospectively and could, in parts, not be fully evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Early fragment removal, especially in joints with dorsal fragmentation, can be beneficial to avoid future cartilage injuries in equine athletes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/evj.13937","type":"journal-article","created":{"date-parts":[[2023,3,16]],"date-time":"2023-03-16T02:31:51Z","timestamp":1678933911000},"page":"89-98","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of cartilage injury in horses with osteochondral fragments in the metacarpo\u2212\/metatarsophalangeal joint: A study on 823 arthroscopies"],"prefix":"10.1111","volume":"56","author":[{"ORCID":"http:\/\/orcid.org\/0000-0002-3256-6055","authenticated-orcid":false,"given":"Janna Evelina Cornelia","family":"Goldkuhl","sequence":"first","affiliation":[{"name":"Pferdeklinik Bargteheide Bargteheide Germany"}]},{"given":"Yury","family":"Zablotski","sequence":"additional","affiliation":[{"name":"Clinic for Horses at the Centre for Clinical Veterinary Medicine, Faculty of Veterinary Medicine Ludwig Maximilians University Munich Germany"}]},{"given":"Volker","family":"Sill","sequence":"additional","affiliation":[{"name":"Pferdeklinik Bargteheide Bargteheide Germany"}]},{"given":"Werner","family":"Jahn","sequence":"additional","affiliation":[{"name":"Pferdeklinik Bargteheide Bargteheide Germany"}]},{"given":"Ina","family":"Lorenz","sequence":"additional","affiliation":[{"name":"Pferdeklinik Bargteheide Bargteheide Germany"}]},{"given":"Jan","family":"Brunk","sequence":"additional","affiliation":[{"name":"Pferdeklinik Bargteheide Bargteheide Germany"}]},{"ORCID":"http:\/\/orcid.org\/0000-0001-8802-7117","authenticated-orcid":false,"given":"Kerstin","family":"Gerlach","sequence":"additional","affiliation":[{"name":"Department for Horses, Faculty of Veterinary Medicine University of Leipzig Leipzig Germany"}]},{"given":"Antonia","family":"Troillet","sequence":"additional","affiliation":[{"name":"Department for Horses, Faculty of Veterinary Medicine University of Leipzig Leipzig Germany"}]}],"member":"311","published-online":{"date-parts":[[2023,3,27]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0737-0806(06)81285-2"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.2011.00434.x"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.12027"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516403776014325"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-7234-3693-5.00005-9"},{"key":"e_1_2_14_7_1","first-page":"1186","article-title":"Osteochondritis dissecans of the sagittal ridge of the third metacarpal and metatarsal bones in horses","volume":"186","author":"Yovich JV","year":"1985","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_14_8_1","first-page":"547","article-title":"Management of osteochondritis dissecans of the dorsal aspect of the distal metacarpus and metatarsus","volume":"25","author":"McIlwraith CW","year":"1990","journal-title":"Proc Annu Conv Am. 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