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{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T10:53:04Z","timestamp":1701082384204},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2022,11,22]],"date-time":"2022-11-22T00:00:00Z","timestamp":1669075200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,2,16]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>Atrial fibrillation (AF) is a global health problem with high morbidity and mortality. Catheter ablation (CA) can reduce AF burden and symptoms, but AF recurrence (AFr) remains an issue. Simple AFr predictors like P-wave duration (PWD) could help improve AF therapy. This updated meta-analysis reviews the increasing evidence for the association of AFr with PWD and offers practical implications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>Publication databases were systematically searched and cohort studies reporting PWD and\/or morphology at baseline and AFr after CA were included. Advanced interatrial block (aIAB) was defined as PWD \u2265 120 ms and biphasic morphology in inferior leads. Random-effects analysis was performed using the Review Manager 5.3 and R programs after study selection, quality assessment, and data extraction, to report odds ratio (OR) and confidence intervals. : Among 4175 patients in 22 studies, 1138 (27%) experienced AFr. Patients with AFr had longer PWD with a mean pooled difference of 7.8 ms (19 studies, P &lt; 0.001). Pooled OR was 2.04 (1.16\u20133.58) for PWD &gt; 120 ms (13 studies, P = 0.01), 2.42 (1.12\u20135.21) for PWD &gt; 140 ms (2 studies, P = 0.02), 3.97 (1.79\u20138.85) for aIAB (5 studies, P &lt; 0.001), and 10.89 (4.53\u201326.15) for PWD &gt; 150 ms (4 studies, P &lt; 0.001). There was significant heterogeneity but no publication bias detected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>P-wave duration is an independent predictor for AF recurrence after left atrium ablation. The AFr risk is increasing exponentially with PWD prolongation. This could facilitate risk stratification by identifying high-risk patients (aIAB, PWD &gt; 150 ms) and adjusting follow up or interventions.<\/jats:p><\/jats:sec>","DOI":"10.1093\/europace\/euac210","type":"journal-article","created":{"date-parts":[[2022,11,22]],"date-time":"2022-11-22T19:20:06Z","timestamp":1669144806000},"page":"450-459","source":"Crossref","is-referenced-by-count":9,"title":["P-wave duration and atrial fibrillation recurrence after catheter ablation: a systematic review and meta-analysis"],"prefix":"10.1093","volume":"25","author":[{"given":"Stergios","family":"Intzes","sequence":"first","affiliation":[{"name":"Democritus University of Thrace, Medical School , Alexandroupoli , Greece"}]},{"given":"Konstantinos","family":"Zagoridis","sequence":"additional","affiliation":[{"name":"Democritus University of Thrace, Medical School , Alexandroupoli , Greece"}]},{"given":"Marianthi","family":"Symeonidou","sequence":"additional","affiliation":[{"name":"Democritus University of Thrace, Medical School , Alexandroupoli , Greece"}]},{"ORCID":"http:\/\/orcid.org\/0000-0003-4985-5862","authenticated-orcid":false,"given":"Emmanouil","family":"Spanoudakis","sequence":"additional","affiliation":[{"name":"Democritus University of Thrace, Medical School , Alexandroupoli , Greece"}]},{"given":"Arash","family":"Arya","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology, Heart Center, University of Leipzig , Struempellstr. 39, 04289 Leipzig , Germany"}]},{"given":"Borislav","family":"Dinov","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology, Heart Center, University of Leipzig , Struempellstr. 39, 04289 Leip
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