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{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T05:26:32Z","timestamp":1703654792928},"reference-count":38,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T00:00:00Z","timestamp":1681776000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/ASMCopyrightv2"},{"start":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T00:00:00Z","timestamp":1681776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["03ZZ0826"]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["03ZZ0835A","03ZZ0803A"]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["03ZZ0803B"]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2023,4,18]]},"abstract":"<jats:p>\n Tuberculosis (TB), caused by\n <jats:named-content content-type=\"genus-species\">Mycobacterium tuberculosis<\/jats:named-content>\n , is the world\u2019s leading cause of mortality from a single bacterial pathogen. With increasing frequency, emergence of drug-resistant mycobacteria leads to failures of standard TB treatment regimens.\n <\/jats:p>","DOI":"10.1128\/aac.01438-22","type":"journal-article","created":{"date-parts":[[2023,3,28]],"date-time":"2023-03-28T14:04:49Z","timestamp":1680012289000},"update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":4,"title":["Pharmacokinetics and Efficacy of the Benzothiazinone BTZ-043 against Tuberculous Mycobacteria inside Granulomas in the Guinea Pig Model"],"prefix":"10.1128","volume":"67","author":[{"given":"Emmelie","family":"Eckhardt","sequence":"first","affiliation":[{"name":"Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald, Germany"}]},{"given":"Yan","family":"Li","sequence":"additional","affiliation":[{"name":"Transfer Group Anti-infectives, Leibniz Institute for Natural Product Research and Infection Biology, Leibniz-HKI, Jena, Germany"}]},{"given":"Svenja","family":"Mamerow","sequence":"additional","affiliation":[{"name":"Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Jena, Germany"}]},{"given":"Jan","family":"Schink\u00f6the","sequence":"additional","affiliation":[{"name":"Institute of Veterinary Pathology, Faculty of Veterinary Medicine, Leipzig University, Leipzig, Germany"}]},{"given":"Julia","family":"Sehl-Ewert","sequence":"additional","affiliation":[{"name":"Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald, Germany"}]},{"given":"Julia","family":"Dreisbach","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and Tropical Medicine, University Hospital of the University of Munich (LMU), Munich, Germany"},{"name":"German Center for Infection Research (DZIF), Partner Site Munich, Munich, Germany"}]},{"given":"Bj\u00f6rn","family":"Corleis","sequence":"additional","affiliation":[{"name":"Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald, Germany"}]},{"given":"Anca","family":"Dorhoi","sequence":"additional","affiliation":[{"name":"Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald, Germany"}]},{"given":"Jens","family":"Teifke","sequence":"additional","affiliation":[{"name":"Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald, Germany"}]},{"given":"Christian","family":"Menge","sequence":"additional","affiliation":[{"name":"Friedrich-Loeff