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{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,1,2]],"date-time":"2023-01-02T05:52:44Z","timestamp":1672638764842},"reference-count":40,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rofo"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>\n Background\u2002Percutaneous hepatic perfusion (CS-PHP) is a treatment option for primary and secondary liver neoplasms and subject of intensive research. This present article provides an overview of CS-PHP regarding patient safety, feasibility and effectiveness based on recent studies.<\/jats:p><jats:p>\n Method\u2002We performed a PubMed search including the search terms chemosaturation, hepatic chemosaturation, percutaneous perfusion and melphalan.<\/jats:p><jats:p>\n Results and conclusion\u2002CS-PHP is a promising procedure for the treatment of uveal melanoma and cholangiocellular carcinoma. There are insufficient data regarding the effectiveness of CS-PHP with respect to other tumor entities. Since CS-PHP can be accompanied by multiple transient side effects and complications, close interdisciplinary cooperation is necessary.<\/jats:p><jats:p>\n Key Points:\n <\/jats:p><jats:p>\n Citation Format\n <\/jats:p>","DOI":"10.1055\/a-1858-3418","type":"journal-article","created":{"date-parts":[[2022,8,17]],"date-time":"2022-08-17T23:11:03Z","timestamp":1660777863000},"page":"30-37","source":"Crossref","is-referenced-by-count":0,"title":["Chemosaturation of the Liver \u2013 an Update"],"prefix":"10.1055","volume":"195","author":[{"ORCID":"http:\/\/orcid.org\/0000-0001-6856-6455","authenticated-orcid":false,"given":"Sebastian","family":"Ebel","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr diagnostische und interventionelle Radiologie, Leipzig University, Leipzig, Germany"}]},{"ORCID":"http:\/\/orcid.org\/0000-0002-0070-3406","authenticated-orcid":false,"given":"Manuel Florian","family":"Struck","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr An\u00e4sthesiologie und Intensivtherapie, Leipzig University, Leipzig, Germany"}]},{"given":"Florian","family":"van Boemmel","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin II, Sektion f\u00fcr Hepatologie, Leipzig University, Leipzig, Germany"}]},{"given":"Anne Bettina","family":"Beeskow","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr diagnostische und interventionelle Radiologie, Leipzig University, Leipzig, Germany"}]},{"given":"Holger","family":"G\u00f6\u00dfmann","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr diagnostische und interventionelle Radiologie, Leipzig University, Leipzig, Germany"}]},{"given":"Timm","family":"Denecke","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr diagnostische und interventionelle Radiologie, Leipzig University, Leipzig, Germany"}]}],"member":"194","published-online":{"date-parts":[[2022,8,17]]},"reference":[{"key":"ref2","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1007\/s00270-019-02177-x","article-title":"Safety of Percutaneous Hepatic Perfusion with Melphalan in Patients with Unresectable Liver Metastases from Ocular Melanoma Using the Delcath Systems\u2019 Second-Generation Hemofiltration System: A Prospective Non-randomized Phase II Trial","volume":"42","author":"T S Meijer","year":"2019","journal-title":"Cardiovasc Intervent Radiol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1441","DOI":"10.1007\/s00270-019-02243-4","article-title":"Chemosaturation Percutaneous Hepatic Perfusion (CS-PHP) with Melphalan: Evaluation of 2D-Perfusion Angiography (2D-PA) for Leakage Detection of the Venous Double-Balloon Catheter","volume":"42","author":"C LA Dewald","year":"2019","journal-title":"Cardiovasc Intervent Radiol"},{"key":"ref4","doi-asserted-by":"publisher","first-pa
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